000 | 02234nam a22003378i 4500 | ||
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001 | CR9781139049627 | ||
003 | UkCbUP | ||
005 | 20170526205634.0 | ||
006 | m|||||o||d|||||||| | ||
007 | cr|||||||||||| | ||
008 | 110307s2011||||enk o ||1 0|eng|d | ||
020 | _a9781139049627 (ebook) | ||
020 | _z9780521769501 (hardback) | ||
040 |
_aUkCbUP _beng _erda _cUkCbUP |
||
050 | 0 | 0 |
_aQP301 _b.V53 2012 |
082 | 0 | 0 |
_a612.7 _223 |
100 | 1 |
_aViceconti, Marco, _eauthor. |
|
245 | 1 | 0 |
_aMultiscale Modeling of the Skeletal System / _cMarco Viceconti. |
264 | 1 |
_aCambridge : _bCambridge University Press, _c2011. |
|
300 |
_a1 online resource (222 pages) : _bdigital, PDF file(s). |
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336 |
_atext _btxt _2rdacontent |
||
337 |
_acomputer _bc _2rdamedia |
||
338 |
_aonline resource _bcr _2rdacarrier |
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500 | _aTitle from publisher's bibliographic system (viewed on 28 Feb 2017). | ||
520 | _aIntegrative approaches to biomedical research promise to advance our understanding of the human body and physiopathology of diseases. In this book, the author focuses on the skeletal system, demonstrating how multiscale modeling can determine the relationship between bone mechanics and disease. Introductory chapters explain the concept of integrative research, what a model is, predictive modeling, and the computational methods used throughout the book. Starting with whole body anatomy, physiology and modeling, subsequent chapters scale down from bone and tissue levels to the cellular level, where the modeling of mechanobiological processes is addressed. Finally, the principles are applied to address truly complex, multiscale interactions. Special attention is given to real-world clinical applications: one in pediatric skeletal oncology and one on the prediction of fracture risks in osteoporotic patients. This book has wide interdisciplinary appeal and is a valuable resource for researchers in mechanical and biomedical engineering, quantitative physiology and computational biology. | ||
650 | 0 | _aMultiscale modeling | |
650 | 0 | _aModels, Biological | |
650 | 0 | _aMusculoskeletal Physiological Phenomena | |
776 | 0 | 8 |
_iPrint version: _z9780521769501 |
856 | 4 | 0 | _uhttps://doi.org/10.1017/CBO9781139049627 |
999 |
_c123913 _d123913 |